Humic acids are formed by the decomposition of organic residues. Thanks to their properties, they act as the “glue” of soil colloids, binding insoluble ions and releasing them as plants require. Humic acids modify soil structure, preventing water loss and erosion in sandy soils and improving aeration in compact soils. They have a beneficial effect on seed germination, their viability. In addition to the effect on germination and plant growth, the effect of humic acids on the multiplication of beneficial soil microorganisms, as well as stimulating the immune system of plants can also be observed. They have the ability to bind insoluble metal ions, oxides and hydroxides and release them slowly as needed by the plant. Due to their properties, we can speak of three types of action: physical, chemical and biological.
  • modify the soil structure, 
  • increase the water holding capacity of the soil and thus reduce the risk of drought,
  • prevent soil cracking, surface water runoff and soil erosion by increasing the water binding capacity of colloids,
  • improve structure, prevent water and nutrient loss in light sandy soils,
  • loosen compact soils and improve their aeration,
  • a darker soil color increases the absorption of solar energy.
  • neutralize the soil pH,
  • enrich the soil with mineral and organic substances,
  • improve nutrient and water availability to plants,
  • retains water-soluble mineral fertilizers in the root zone and reduces their leaching,
  • acts as a natural chelating agent for metal ions in alkaline environments and facilitates their uptake by the root system,
  • have a very high colloid exchange capacity,
  • increase the conversion of nutrients (NPK and micronutrients) to plant-available forms,
  • increase nitrogen uptake by the plant,
  • help eliminate chlorosis caused by lack of iron,
  • reduce the availability of toxic substances from the soil.
  • stimulate plant growth by accelerating cell division,
  • act as organic catalysts for many biological processes.
  • stimulate plant enzymes and increase their production,
  • increase the natural resistance of plants to diseases and pests,
  • stimulate root growth, especially vertical roots, thus increasing nutrient uptake,
  • increase root respiration,
  • support photosynthesis,
  • increase seed germination and viability,
  • stimulate growth and multiplication of beneficial soil microorganisms.

Chitozn is a natural, non-toxic, biodegradable and biofunctional polymer, safe for the human body and the environment.  It is obtained from the shells of marine crustaceans by deacetylation of chitin, which, after cellulose, is the most abundant organic material found in nature. It shows antibacterial, antifungal and antioxidant properties.

  • lowers cholesterol levels
  • increases the body’s immune system by increasing T-lymphocyte activity
  • lowers blood pressure
  • favourably influences intestinal peristalsis
  • eliminates hyperacidity and flatulence
  • regulates the pancreas and liver
  • cleanses the body of toxins, heavy metals and other harmful substances
  • stimulates collagen production
  • accelerates wound and sunburn healing
  • prevents the formation of scars
  • alleviates changes after insect bites
  • inhibits the skin aging process
  • prevents moisture loss through the skin
  • Protects against free radicals and microorganisms.
  • has a positive effect on crop quality and yield
  • stimulates the natural immunity of plants in the fight against pathogens.
  • stimulates root system development
  • used in the form of spraying produces a kind of film on the plant to prevent excessive evaporation of water, as well as a barrier against pests.
  • protects plants from stress.

Chitosan is a polymer commonly found in nature. It is obtained from chitin, which is a structural material of crustaceans (shrimps, crabs, crayfish, krill), insects, fungi and bacteria. It is a polysaccharide with a molecular structure very similar to cellulose. As a compound of natural origin, non-toxic and biodegradable, it is completely safe for the environment.

In terms of chemical structure, it is a polysaccharide composed of many amino sugar molecules, connected to each other by β 1-4 bonds. This amino sugar is chitosamine (D-glucosamine), which is a derivative of D-glucose, in which the OH group in the second position has been substituted with an amino group (NH2). In comparison, cellulose is a polysaccharide composed of D-glucose molecules also linked by a β1-4 bond.

The term chitosan is used for compounds formed by deacetylation of chitin as a result of the action of concentrated alkali at elevated temperature, which leads to a gradual elimination of acetate groups and formation of free amino groups in the glycosidic rings of the biopolymer.

It is assumed that in its natural form chitin occurs in a partially acetylated form i.e. through OH or NH2 groups the acetyl group CH3-C=o is attached ( furda 1983).

Interestingly, despite its close affinity to cellulose, chitin does not occur in higher plants. However, it shows high biological activity in relation to it, e.g. increasing the resistance of plants to unfavourable environmental conditions, to fungal and bacterial infections.


Effects of chitosan oligomers on human health:

Researchers have shown that the substances discovered are polymeric inhibitors. They were created on the basis of chitosan – a compound obtained from marine crustaceans. The effect of the polymer is that it binds to the protein that forms the “crown” of the virus and blocks its interaction with the cell receptor, and consequently the entry of the virus into the cell. 

Chitosan, from which polymeric compounds are obtained, is chemically an organic compound of the polysaccharide group; a derivative of chitin, formed by its partial deacetylation.
Deacetylation of chitin involves the removal of acetyl groups from chitin, which harden and cement chitin. The highest biochemical activity of chitosan is obtained when it is processed through the patented OCHG™ process. The result is chitosan lactate or chitosan in the form of oligomers, or polymers, with short chains and a well-defined molecular weight. Structurally, chitosan is a cellulose (fiber) of animal origin, similar to human fibrin. It is completely natural and well tolerated by our body.
Chitosan has a very beneficial effect on the entire body. Experts call it the sixth essential component of life after proteins, fats, sugars, minerals and vitamins. It effectively purifies and deacidifies the body, stimulates the human defense mechanisms, does not allow cancer cells to multiply, lowers cholesterol, helps reduce body weight. With the help of chitosan it is possible to overcome many diseases with which modern medicine cannot cope.

CHITOZIN FIT C contains liquid chitosan lactate in the form of oligomers. It is characterized by very high bioavailability and biochemical activity, which gives it the highest effectiveness among other known products containing chitosan.

Experimental studies confirm the antimicrobial mechanism of action of chitosan. It is related to the breakdown of the cell wall structure due to free amino groups present in chitosan. The positively charged chitosan interacts with the negatively charged chemical bonds in the cell wall of bacteria or viruses, causing them to break down. This occurs through electrostatic forces acting between protonated amino groups and negative residues, competing for electro-negative sites on the surface of the microbial cell membrane. This interaction alters
permeability of the cell membrane, and contributes to its breakdown and leakage of intracellular matter.

Other studies suggest that a polymeric envelope forms around the cell membrane of microorganisms, that is, chitosan forms a kind of shell over the microorganism cell that prevents
nutrients from entering that cell. Another discovered mechanism of action of Chitosan is the binding of chitosan molecules to microbial or viral DNA, which leads to
inhibition of mRNA and protein synthesis.

Chitosan molecules have been shown to be able to penetrate the cell wall of bacteria and reach their genetic material.

It works on all organs, improves the general condition of the body, raising the pH to 7.35 – 7.4. deacidifies the body. Acidification of the body disrupts all biochemical processes of the body, thickens the blood, disrupts circulation, puts a great strain on the kidneys, causes joint and muscle pain, and promotes the growth of cancer cells. In an alkaline environment, cancer cells do not reproduce. Therefore, chitosan used in higher doses causes cancer cell death and reduces the size of tumors

Chitosan cleanses the digestive tract, liver and entire body of heavy metals and toxins by binding and excreting them from the body. Research results indicate that it is very effective in improving the condition and function of the liver and pancreas. Chitosan also binds chlorine ions from table salt and excretes them, which prevents the production of angiotensin, a substance that causes rapid vasoconstriction. As a result, it has a hypotensive effect, lowering blood pressure.

The formula binds and excretes cholesterol from the gastrointestinal tract because it has positively charged amino groups at the same pH as the gastrointestinal tract. The amino groups bind to negatively charged molecules such as lipids and bile, preventing their absorption and storage by the body.

The action of chitosan in lowering LDL cholesterol can be explained by the theory that chitosan salts react with fatty acids and bind lipids by a mechanism of hydrophobic interaction. The lipids so bound are excreted from the gastrointestinal tract along with other metabolic products, rather than being reabsorbed as if they occurred naturally.

When it dissolves, a coating is formed which acts as a shield, eliminates hyperacidity, stimulates healing processes, heals erosions, ulcers and mucosal defects. Mucosal defects are the cause of Leaky Gut Syndrome.

Leaky Gut Syndrome is one of the main causes of allergies and autoimmune diseases, because undigested nutrients (e.g. casein, gluten) and toxins, penetrate through holes in the intestinal mucosa, enter the bloodstream and consequently trigger an immune response from the immune system

Leaky gut syndrome is often caused by Candida yeast. Candida albicans is a parasitic fungus that lives in the human digestive tract. If there is dysbiosis, or a disruption in the normal composition of the intestinal microbiota, candida begins to proliferate and dominate. As a result, they secrete a number of toxins and metabolites that enter the bloodstream and poison the entire body. This adversely affects a number of processes in the body, disrupts its functioning leading to diseases, including cancer. Chitosan oligomers effectively inhibit Candida.

Hyaluronic acid is also a major component of joint synovia. It is responsible for the viscosity of the synovium, lubricating joint surfaces and nourishing cartilage. Therefore, chitosan used for longer periods of time improves joint mobility.

  • They strengthen the body’s immunity by increasing the activity of T lymphocytes,
  • They inhibit infections with pathogenic microorganisms,
  • They eliminate acidification of the organism, increase the pH by alkaline action,
  • They have anti-cancer properties, inhibit the proliferation of cancer cells and the formation of metastases,
  • They cleanse the body of heavy metals and other harmful substances (mercury, cadmium, pesticides, artificial colors,
  • Has antihypertensive effect – lowers blood pressure, reduces capillary contractility,
  • Lower cholesterol, lowers the absorption of fats and cholesterol in the intestines, cleans blood vessels from cholesterol plaques
  • They improve the functioning of the liver and pancreas
  • They help control blood sugar levels,
  • They protect the mucous membranes of the digestive tract, effectively accelerate the healing of erosions and ulcers,
  • They fight leaky gut syndrome – one of the leading causes of allergies and autoimmune diseases,
  • Eliminate heartburn, acidity and gas,
  • They improve the condition of the intestinal microbiota – they cleanse intestinal villi, improve intestinal peristalsis,
  • Increases skin elasticity and joint mobility, strengthens connective and cartilage tissue
  • with decreased immunity and immune disorders,
  • in cancer prevention, chemotherapy, radiotherapy, intoxication,
  • in the prevention of cardiovascular disease; atherosclerosis, infarcts, strokes,
  • in hypertension,
  • in abnormal liver and pancreas and diabetes,
  • acidity and heartburn,
  • in inflammation, erosions and ulcerations of the gastrointestinal tract,
  • gastrointestinal yeasts,
  • food poisoning

CHITOZIN FIT C should not be used by people allergic to shellfish. It is also not recommended for children under 12 years of age. It is necessary to keep a 2-hour break between taking the preparation containing chitosan and other used preparations and medicines, because it is an absorbent and may reduce their assimilation.

Take 3 times a day, 5 ml (teaspoon) per ½ glass of water, preferably morning and evening and before food.

For preventive purposes 1-2 months 2-3 times a year.

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Majeti N.V. Ravi Kumar A reviev of chitin and chitosan applications. Reactive & Functional Polymers 46 2000) 1-27.

Alemdaroglu C., Zelihagul D., Celebi N., Zor F., Ozturk S., Erdogan D. 2006. An investigation on burn wound healing in rats with chitosan gel formulation containg epidermal growth factor. Burns 32, s. 219-327.

Ignacak J., Wiśniewska-Wrona M.,Pałka I.,Zagajewski J., Niekraszewicz A. 2011. Rola oligomerów chitozanowych w regulacji proliferacji komórek nowotworowych wodobrzusza Ehrlicha in vitro. Progress on chemistry and application of chitin and its derivatives, Monografia, t. XVI, Polskie Towarzystwo Chitynowe, s. 89.

Ravi Kumar N. V. 2000. A review of chitin and chitosan applications. Reactive & Functional Polymers, 46, s.1-27.

Muzzarelli R.A.A., Muzzarelli C. 2005. Chitosan Chemistry: Relevance to the Biomedical Science. Springer Heidelberg, Berlin.

Ming-Tsung Y., Joan-Hwa Y., Yeng-Leun M. 2008. Antioxidante properties of chitosan from crab shells. Carbohydrate Polymers, 74,4, s.840-844.

Obara K., Ishihara M., Ishizuka T., Fujita M., Ozeki Y., Maehara T., Saito Y.,Yura H., Matsui T., Hattori

H., Kikuchi M., Kurita A. 2003. Photocrosslinkable chitosan hydrogel containing fibroblast growth factor-2 stimulates wound healing in healing-impaired db/db mice. Biomaterials, 24, 3437-3444.

Schmitt F., Lagopoulos L., Käuper P., Rossi N., Busso N., Barge J., Wagnières G., Laue C., Wandrey C., Juillerat-Jeanneret L. 2010. Nanożele na bazie chitozanu do selektywnego dostarczania fotouczulaczy do
Nanożele na bazie chitozanu do selektywnego dostarczania fotouczulaczy do makrofagów i ulepszonej retencji w stawach i terapii stawów. Journal Control Research. 1;144(2):242-50.

Sahm Inan D., Unver Saraydm D. 2013. Investigation of the wound healing effects of chitosan on FGFR3 and VEGF immunlocalization in experimentally diabetic rats. International Journal of Biomedical Materials
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